[HTML][HTML] TSNA exposure from cigarette smoking: 18 years of urinary NNAL excretion data
S Appleton, RM Olegario, PJ Lipowicz - Regulatory toxicology and …, 2014 - Elsevier
The objective of this work was to characterize trends over time in urinary excretion of 4-
(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) among cigarette smokers in the US. We
identified 35 studies presenting data that either reported, or could be converted to, common
units of total urinary NNAL excretion as pmol/mg creatinine. The studies spanned 18 years,
reported urinary NNAL excretion estimates for 61 defined populations, and included a
combined total of 3941 study participants. Analyses show that urinary NNAL excretion trends …
(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) among cigarette smokers in the US. We
identified 35 studies presenting data that either reported, or could be converted to, common
units of total urinary NNAL excretion as pmol/mg creatinine. The studies spanned 18 years,
reported urinary NNAL excretion estimates for 61 defined populations, and included a
combined total of 3941 study participants. Analyses show that urinary NNAL excretion trends …
[PDF][PDF] TSNA exposure from cigarette smoking: 18 Years of urinary NNAL
S Appleton - 2013 - cyberleninka.org
abstract 25 The objective of this work was to characterize trends over time in urinary
excretion of 4-(methylnitros-26 amino)-1-(3-pyridyl)-1-butanol (NNAL) among cigarette
smokers in the US. We identified 35 studies pre-27 senting data that either reported, or could
be converted to, common units of total urinary NNAL excretion 28 as pmol/mg creatinine.
The studies spanned 18 years, reported urinary NNAL excretion estimates for 61 29 defined
populations, and included a combined total of 3941 study participants. Analyses show that …
excretion of 4-(methylnitros-26 amino)-1-(3-pyridyl)-1-butanol (NNAL) among cigarette
smokers in the US. We identified 35 studies pre-27 senting data that either reported, or could
be converted to, common units of total urinary NNAL excretion 28 as pmol/mg creatinine.
The studies spanned 18 years, reported urinary NNAL excretion estimates for 61 29 defined
populations, and included a combined total of 3941 study participants. Analyses show that …
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